HuagongsheHuagongshe Chemistry Print Report · For research reference only
hexahydro-2H-cyclopenta[b]furan-2-one → 3-Octanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | hexahydro-2H-cyclopenta[b]furan-2-one | HCID 11665410 | — |
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 3-Octanol | HCID 11527 | — |
Reaction Steps
The compound (52) (12.1 g) was reduced with diisobutylaluminum hydride (1.5M, 65.1 ml) in toluene (500 ml) at -78° C. and the obtained crude product was subjected to silicagel column chromatography to give the titled compound (53). Yield: 11.1 g (91%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05686487 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-f3d81bbb58614820bada496856e44850 |
| Source note | uspto-grants-1997_11 |