HCID 21476972, compound → HCID 21476978, compound

HRID 2293605Notes

Reaction equation

C(COC1C=C(OC)C=CC=1CN1C2C(=CC(O)=CC=2)C(C2C=CC3OCOC=3C=2)=C1C(OCC)=O)(OCC)=O.[CH2:41]([O:48][C:49]1[CH:50]=[C:51]2[C:55](=[CH:56][CH:57]=1)[N:54]([CH2:58][C:59]1[CH:64]=[CH:63][C:62]([O:65][CH3:66])=[CH:61][C:60]=1[O:67][CH2:68][C:69]([O:71]CC)=[O:70])[C:53]([C:74]([O:76]CC)=[O:75])=[C:52]2[C:79]1[CH:84]=[CH:83][C:82]2[O:85][CH2:86][O:87][C:81]=2[CH:80]=1)[C:42]1C=CC=C[CH:43]=1>>[C:69]([CH2:68][O:67][C:60]1[CH:61]=[C:62]([O:65][CH3:66])[CH:63]=[CH:64][C:59]=1[CH2:58][N:54]1[C:55]2[C:51](=[CH:50][C:49]([O:48][CH2:41][CH2:42][CH3:43])=[CH:57][CH:56]=2)[C:52]([C:79]2[CH:84]=[CH:83][C:82]3[O:85][CH2:86][O:87][C:81]=3[CH:80]=2)=[C:53]1[C:74]([OH:76])=[O:75])([OH:71])=[O:70]

Participants

Reactant 2

HCID 21476972HCID 21476972, compound

HCID 21476975HCID 21476975, compound

Product 1

HCID 21476978HCID 21476978, compound

Procedure

Ethyl 1-(2-carboethoxymethoxy-4-methoxybenzyl)-5-hydroxy-3-(3,4-methlenedioxyphenyl)indole-2-carboxylate. The title compound was prepared from ethyl 5-benzyloxy-1-(2-carboethoxymethoxy-4-methoxybenzyl)-3-(3,4-methylenedioxyphenyl)indole-2-carboxylate (460 mg, 0.735 mmol) by the method given in example 6; m.p. 128°-130° C.

Sources & evidence

ORD record: ord-f2fef7f6434444779f70bc604e07d0af
Source dataset: uspto-grants-1997_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05686481

Reaction notes

Loading…