Thionyl Chloride → 3-Chloromethylpyridinium hydrochloride

HRID 2293712Notes

Reaction equation

S(Cl)([Cl:3])=O.[ClH:5].O[CH2:7][C:8]1[CH:9]=[NH+:10][CH:11]=[CH:12][CH:13]=1>>[ClH:3].[Cl:5][CH2:7][C:8]1[CH:9]=[NH+:10][CH:11]=[CH:12][CH:13]=1

Participants

Reactant 2

HCID 24386Thionyl Chloride

HCID 214777763-Hydroxymethyl pyridinium hydrochloride

Product 1

HCID 214777733-Chloromethylpyridinium hydrochloride

Procedure

reacting thionyl chloride with 3-hydroxymethyl pyridinium hydrochloride to form 3-chloromethyl pyridinium hydrochloride, at least a portion of which forms as a solid in the reaction mixture.

Sources & evidence

ORD record: ord-718b63d267ae4aeea2388e2bd2cff69e
Source dataset: uspto-grants-1997_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05686619

Reaction notes

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