N-bromobutanimide → HCID 12519668, compound

Participants

Reaction Conditions

Reaction Steps

N-Bromosuccinimide (20.7 g) was added to a stirred solution of 5,5-dimethyl-2-phenyl-1,3-dioxane (19.2 g) in 200 mL of CCl4 containing 8.5 g of BaCO3 in suspension. The mixture was heated to reflux under Ar for 2.2 h, then cooled to 24° C. over 15 h, filtered and concentrated. The residue was partitioned between ether and water, and the ethereal solution was washed with brine, dried (MgSO4), filtered and concentrated to give 24.8 g of a yellow oil which was stored in the dark at 0° C. under Ar.

Provenance & Evidence