Chlorosuccinimide → HCID 86751613, compound

Participants

Reaction Steps

To a solution of the product of Example 57 (400 mg, 1.3 mmol) in pyridine (15 mL) was added N-chlorosuccinimide (200 mg, 1.5 mmol) and the solution was heated at 90°-95° C. for 30 min under nitrogen. All volatiles were removed in vacuo and the oily residue was chromatographed on silica gel using CH2Cl2 /3% MeOH as eluent to give the product (390 mg, 87%) as a colorless oil:

Provenance & Evidence