2,4-Dimethoxybenzoyl chloride → HCID 69063904, compound

HRID 229395Notes

Reaction equation

HRID 229395 reaction equation
[CH2:1]([CH:3]1[NH:12][C:11]2[C:6](=[CH:7][CH:8]=[C:9]([F:13])[CH:10]=2)[N:5]2[CH:14]=[CH:15][CH:16]=[C:4]12)[CH3:2].[CH3:17][O:18][C:19]1[CH:27]=[C:26]([O:28][CH3:29])[CH:25]=[CH:24][C:20]=1[C:21](Cl)=[O:22]>>[CH3:17][O:18][C:19]1[CH:27]=[C:26]([O:28][CH3:29])[CH:25]=[CH:24][C:20]=1[C:21]([N:12]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([F:13])[CH:10]=2)[N:5]2[CH:14]=[CH:15][CH:16]=[C:4]2[CH:3]1[CH2:1][CH3:2])=[O:22]

Participants

3

Reactant 2

HCID 27347192,4-Dimethoxybenzoyl chlorideHCID 69064457HCID 69064457, compound

Product 1

HCID 69063904HCID 69063904, compound

Procedure

5-(2,4-Dimethoxybenzoyl)-4-ethyl-7-fluoro-4,5-dihydropyrrolo[1,2-a]quinoxaline was prepared from the product of Example 17 and 2,4-dimethoxy benzoyl chloride according to the procedure of Example 106, Step 2, mp 131-132° C. MS (ESI) m/z 381; Anal. Calcd for C22H21FN2O3: C, 69.46; H, 5.56; N, 7.36. Found: C, 69.22; H, 5.63; N, 7.32.

Sources & evidence

ORD record
ord-e0901d05a1e74bb285928e499595d009
Source dataset
uspto-grants-2009_07
Patent number
US07563793B2

Reaction notes

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