HCID 131720323, compound → HCID 131720322, compound

Participants

Reaction Steps

Dissolve the product of Example 5 (0.266 g, 0.48 mmol) in EtOAc (16 mL), dilute with CH3OH (20 mL) and purge with N2. Add 20% Pd/C (0.05 g), purge the mixture with H2 and then stir under a balloon of H2 overnight. Filter the reaction mixture through celite. Wash the filter cake with EtOAc and concentrate the filtrate to give 0.156 g of the title compound as a colorless oil. HRMS calc'd for C28H28 NO4 :M+H 462.2081; found 462.2070.MS (CI): 462 (M+1,37), 351 (17), 293(41 ), 138(100).

Provenance & Evidence