2,4-Dimethoxybenzoyl chloride → HCID 69063979, compound

HRID 229397Notes

Reaction equation

HRID 229397 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]1[CH:12]=[CH:13][CH:14]=[C:7]1[CH:6]([CH2:15][CH3:16])[N:5]2S(C1C=CC(O)=C(C)C=1)(=O)=O.[CH3:28][O:29][C:30]1[CH:38]=[C:37]([O:39][CH3:40])[CH:36]=[CH:35][C:31]=1[C:32](Cl)=[O:33]>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]1[CH:12]=[CH:13][CH:14]=[C:7]1[CH:6]([CH2:15][CH3:16])[N:5]2[C:32](=[O:33])[C:31]1[CH:35]=[CH:36][C:37]([O:39][CH3:40])=[CH:38][C:30]=1[O:29][CH3:28]

Participants

3

Reactant 2

HCID 27347192,4-Dimethoxybenzoyl chlorideHCID 11509614HCID 11509614, compound

Product 1

HCID 69063979HCID 69063979, compound

Procedure

7-Chloro-5-(2,4-dimethoxybenzoyl)-4-ethyl-4,5-dihydropyrrolo[1,2-a]quinoxaline was prepared from the intermediate of Example 68A and 2,4-dimethoxy benzoyl chloride according to the procedure of Example 106, Step 2 mp 70-74° C. MS (ESI) m/z 397; Anal. Calcd for C22H21ClN2O3: C, 66.58; H, 5.33; N, 7.06. Found: C, 66.34; H, 5.59; N, 6.85.

Sources & evidence

ORD record
ord-ca5fd1544a064bf6bfafb4f4c52e6a34
Source dataset
uspto-grants-2009_07
Patent number
US07563793B2

Reaction notes

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