m-Anisoyl chloride → HCID 69063974, compound

HRID 229398Notes

Reaction equation

HRID 229398 reaction equation
[CH2:1]([CH:3]1[NH:12][C:11]2[C:6](=[CH:7][CH:8]=[C:9]([F:13])[CH:10]=2)[N:5]2[CH:14]=[CH:15][CH:16]=[C:4]12)[CH3:2].[C:17](Cl)(=[O:26])[C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([O:24][CH3:25])[CH:19]=1>>[CH2:1]([CH:3]1[N:12]([C:17](=[O:26])[C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([O:24][CH3:25])[CH:19]=2)[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([F:13])[CH:10]=2)[N:5]2[CH:14]=[CH:15][CH:16]=[C:4]12)[CH3:2]

Participants

3

Reactant 2

HCID 74374m-Anisoyl chlorideHCID 69064457HCID 69064457, compound

Product 1

HCID 69063974HCID 69063974, compound

Procedure

4-Ethyl-7-fluoro-5-(3-methoxybenzoyl)-4,5-dihydropyrrolo[1,2-a]quinoxaline was prepared from the product of Example 17 and m-anisoyl chloride according to the procedure of Example 106, Step 2 mp 70-74° C. MS (ESI) m/z 351; Anal. Calcd for C21H19FN2O2: C, 71.99; H, 5.47; N, 7.99. Found: C, 70.08; H, 5.55; N, 7.14.

Sources & evidence

ORD record
ord-661c75f5368a4376a59f78ca9b483af4
Source dataset
uspto-grants-2009_07
Patent number
US07563793B2

Reaction notes

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