HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Benzyloxy-benzyl)-cyclopropylamine → 4-((1-Aminocyclopropyl)methyl)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Benzyloxy-benzyl)-cyclopropylamine | HCID 23106121 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-((1-Aminocyclopropyl)methyl)phenol | HCID 59789232 | — |
Reaction Steps
Hydrogenation of 5.00 g (19.7 mmol) 1-(4-benzyloxy-benzyl)-cyclopropylamine in 60 mL methanol at 3 bar with palladium on charcoal as catalyst. Yield: 2.25 g (70%); mass spectroscopy: [M+H]+=164.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07563806B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-3429a2ddff684ff6893259b03df32ca4 |
| Source note | uspto-grants-2009_07 |