HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Difluoromethoxy)-2-nitrobenzene → 2-(Difluoromethoxy)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Difluoromethoxy)-2-nitrobenzene | HCID 2737011 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(Difluoromethoxy)aniline | HCID 934620 | 74,424% |
Reaction Steps
A mixture of 1-difluoromethoxy-2-nitrobenzene (8.21 g, 43.4 mmol) and 10% palladium on carbon (1.1 g) in 100 mL of ethanol was stirred under a hydrogen atmosphere at room temperature for approximately 24 hours. The mixture was filtered and the filtrate was concentrated to give 2-difluoromethoxyaniline (5.14 g, 32.3 mol) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05688795 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-13e38dca0baf48c986d1c223c3f2e5fe |
| Source note | uspto-grants-1997_11 |