Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-5-chloro-n,n-dimethylbenzamide → 5-chloro-2-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino}-N,N-dimethylbenzamide hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-5-chloro-n,n-dimethylbenzamide | HCID 274287 | — |
| 반응물 | 1-(3-Chloropropyl)-4-(2-methoxyphenyl)piperazine | HCID 622669 | — |
| 생성물 | 5-chloro-2-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino}-N,N-dimethylbenzamide hydrochloride | HCID 21473491 | — |
반응 단계
Proceeding as in Example 26, but reacting 1-chloro-3-[4-(2-methoxyphenyl)-piperazin-1-yl]propane with 2-amino-5-chloro-N,N-dimethylbenzamide gave 5-chloro-2-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino}-N,N-dimethylbenzamide hydrochloride, m.p. 100°-108° C.; Anal.: Calcd. for C23H31ClN4O2.(HCl)2.(H2O)0.75 : C, 57.38; H, 7.02; N, 11.65%; Found: C, 57.47; H, 6.94 ; N, 11.48%;
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05688795 |
| 출처 데이터셋 | uspto-grants-1997_11 |
| ORD ID | ord-900e502a1b9a4be39338631fa5465b15 |
| 출처 메모 | uspto-grants-1997_11 |