Hydrochloric Acid → HCID 21473495, compound

Participants

Reaction Steps

A solution of 2-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino}-N,N,3-trimethylbenzamide (70 mg, 0.17 mmol) in 0.5 mL of 5% methanol/methylene chloride was acidified with 0.6 mL of 1M hydrochloric acid in methanol and then ethyl acetate was added to give a precipitate. The supernatant was decanted and the precipitate was washed with ether, collected and dried to give 2-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino}-N,N,3-trimethylbenzamide hydrochloride (75 mg, 0.15 mmol). Anal.: Calcd. for C24H34 N4O2.(HCl)2.(H2O)0.5 : C, 58.53; H, 7.57; N, 11.38%; Found: C, 58.52; H, 7.68; N, 10.99%.

Provenance & Evidence