1-(2-Methoxyphenyl)piperazine → HCID 21473449, compound

HRID 2294150Notes

Reaction equation

HRID 2294150 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]1[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1.[Cl:15][CH2:16][CH2:17][CH2:18][NH:19][C:20]1[CH:30]=[C:29]([O:31][CH3:32])[C:28]([O:33][CH3:34])=[CH:27][C:21]=1[C:22]([N:24]([CH3:26])[CH3:25])=[O:23]>>[ClH:15].[CH3:32][O:31][C:29]1[C:28]([O:33][CH3:34])=[CH:27][C:21]([C:22]([N:24]([CH3:26])[CH3:25])=[O:23])=[C:20]([NH:19][CH2:18][CH2:17][CH2:16][N:12]2[CH2:13][CH2:14][N:9]([C:4]3[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=3[O:2][CH3:1])[CH2:10][CH2:11]2)[CH:30]=1

Participants

3

Reactant 2

HCID 13461-(2-Methoxyphenyl)piperazineHCID 21473486HCID 21473486, compound

Product 1

HCID 21473449HCID 21473449, compound

Procedure

substituting 1-(2-methoxyphenyl)piperazine and 2-(3-chloropropyl)amino-4,5-dimethoxy-N,N-dimethylbenzamide gave 4,5-dimethoxy-2-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino}-N,N,-dimethylbenzamide hydrochloride, m.p. 79°-82° C.; Anal.: Calcd. for C25H36N4O4.HCl.(H2O)0.25 : C, 60.35; H, 7.60; N, 11.26%; Found: C, 60.18H, 7.75; N, 11.35%;

Sources & evidence

ORD record
ord-cb28bfa0308748629513bbc10183488d
Source dataset
uspto-grants-1997_11
Patent number
US05688795

Reaction notes

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