Trifluoroacetate → HCID 59789262, compound

HRID 229416Notes

Reaction equation

HRID 229416 reaction equation
C([O:8][C:9]1[C:14]2[NH:15][C:16](=[O:19])[CH2:17][O:18][C:13]=2[C:12]([C:20](=[O:24])[CH:21](O)O)=[CH:11][CH:10]=1)C1C=CC=CC=1.[NH2:25][C:26]1([CH2:29][C:30]2[CH:35]=[CH:34][C:33]([C:36]3([OH:39])[CH2:38][CH2:37]3)=[CH:32][CH:31]=2)[CH2:28][CH2:27]1.FC(F)(F)C([O-])=O>>[OH:8][C:9]1[C:14]2[NH:15][C:16](=[O:19])[CH2:17][O:18][C:13]=2[C:12]([CH:20]([OH:24])[CH2:21][NH:25][C:26]2([CH2:29][C:30]3[CH:35]=[CH:34][C:33]([C:36]4([OH:39])[CH2:38][CH2:37]4)=[CH:32][CH:31]=3)[CH2:27][CH2:28]2)=[CH:11][CH:10]=1

Participants

4

Reactant 3

HCID 84468TrifluoroacetateHCID 231061485-(benzyloxy)-8-(dihydroxyacetyl)-2H-1,4-benzoxazin-3(4H)-oneHCID 59789252HCID 59789252, compound

Product 1

HCID 59789262HCID 59789262, compound

Procedure

Prepared according to general method 3 from 329 mg (1 mmol) 5-benzyloxy-8-(2,2-dihydroxy-acetyl)-4H-benzo[1,4]oxazin-3-one and 203 mg (1 mmol) 1-[4-(1-amino-cyclopropylmethyl)-phenyl]-cyclopropanol. Yield: 29 mg (6%, trifluoroacetate); mass spectroscopy: [M+H]+=411.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-46f1ffd2bfcc4600b61a704eac918361
Source dataset
uspto-grants-2009_07
Patent number
US07563806B2

Reaction notes

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