HCID 21474325, compound → HCID 21474443, compound

HRID 2294252Notes

Reaction equation

HRID 2294252 reaction equation
C([O:8][C:9]1[C:14](=[O:15])[CH:13]=[CH:12][N:11]([CH2:16][CH2:17][OH:18])[C:10]=1[CH:19]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[O:27]CC1C=CC=CC=1)[OH:20])C1C=CC=CC=1>C(OCC)(=O)C.C(O)C>[OH:8][C:9]1[C:14](=[O:15])[CH:13]=[CH:12][N:11]([CH2:16][CH2:17][OH:18])[C:10]=1[CH:19]([OH:20])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[OH:27]

Participants

3

Reactant 1

HCID 21474325HCID 21474325, compound

Product 1

HCID 21474443HCID 21474443, compound

Reagents, catalysts & solvents 1

HCID 21584252Ethanol ethylacetateSolvent

Procedure

3-Benzyloxy-2-[(2-benzyloxy-phenyl)-hydroxy-methyl]-1-(2-hydroxy-ethyl)-.1H-pyridin-4-one: From 2.42 g of 3-benzyloxy-2-[(2-benzyloxy-phenyl)-(tetrahydropyran-2-yloxy)-methyl]-1-(2.-hydroxy-ethyl)-1H-pyridin-4-one there is obtained analogously to Example 6e, after chromatography: 3-benzyloxy-2-[(2-benzyloxy-phenyl)-hydroxy-methyl]-1-(2-hydroxy-ethyl)-1H-pyridin-4-one. Beige foam. Rf value: 0.17 (silica gel 60, ethyl acetate/ethanol 9/1).

Sources & evidence

ORD record
ord-3555027c943e42ecbc2bc81e47761eaa
Source dataset
uspto-grants-1997_11
Patent number
US05688815

Reaction notes

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