3,4-dihydro-2H-pyran → HCID 21474296, compound

Participants

Reaction Steps

3-Benzyoxy-2-[(4-methylthiophenyl)-(tetrahydropyran-2-yoxy)-methyl]-pyran4-one: Reaction of 16.7 g of 3-benzyloxy-2-[hydroxy-(4-methylthio-phenyl)-methyl]-pyran-4-one with 3,4-dihydro-2H-pyran analogously to Example 1b yields crude 3-benzyloxy-2-[(4-methylthio-phenyl)-(tetrahydro-pyran-2-yloxy)-methyl]-pyran-4-one in the form of a diastereoisomeric mixture. Rf value 0.65 (silica gel 60, hexane/dichloromethanelethyl acetate 1/1/1).

Provenance & Evidence