HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propanol, 1-azido-3-phenoxy- → 1-Amino-3-phenoxypropan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propanol, 1-azido-3-phenoxy- | HCID 2793901 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-Amino-3-phenoxypropan-2-ol | HCID 2725073 | 107.6% |
Reaction Steps
A procedure similar to that described in Preparation 13 was repeated, except that 1.17 g of 3-phenoxy-2-hydroxypropylazide (prepared as described in Preparation 14), 0.46 g of lithium aluminum hydride and 20 ml of anhydrous tetrahydrofuran were used, to give 1.09 g of the title compound, melting at 82° C. to 84° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05688823 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-00846d809a1b4971b31f078750f17e4e |
| Source note | uspto-grants-1997_11 |