Tetrabutylammonium Fluoride → HCID 67741583, compound

Participants

Reaction Steps

A procedure similar to that described in Preparation 5(b) was repeated, except that 2.00 g of 3-[2-t-butyldimethylsilyloxy-1(S)-methylethyl]-5(S)-(3-chlorophenoxymethyl)oxazolidin-2-one (prepared as described in Preparation 39), 15 ml of tetrabutylammonium fluoride (26% w/v in tetrahydrofuran) and 20 ml of anhydrous tetrahydrofuran were used, to give 0.85 g of the title compound, melting at 67° C. to 70° C. and having [α]D =+57.0° (methanol, c=1.055).

Provenance & Evidence