HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Azido-3-(benzyloxy)propan-2-ol → 1-Amino-3-(benzyloxy)propan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Azido-3-(benzyloxy)propan-2-ol | HCID 13210526 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-Amino-3-(benzyloxy)propan-2-ol | HCID 342795 | 70.2% |
Reaction Steps
A procedure similar to that described in Preparation 13 was repeated, except that 5.7 g of 3-benzyloxy-2-hydroxypropylazide (prepared as described in Preparation 47), 2.09 g of lithium aluminum hydride and 250 ml of anhydrous tetrahydrofuran were used, to give 3.5 g of the title compound as white crystals, melting at 72° C. to 74° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05688823 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-23f8285c55874e8aa5e6758bd909de12 |
| Source note | uspto-grants-1997_11 |