4-Hydroxybiphenyl → 1-(Biphenyl-4-yloxy)-2,3-epoxypropane

Participants

Reaction Steps

A procedure similar to that described in preparation 46 was repeated, except that 4.00 g of 4-phenylphenol, 3.97 g of epibromohydrin, 1.27 g of sodium hydride (as a 55% by weight dispersion in mineral oil) and 80 ml of anhydrous dimethylformamide were used, to give 4.43 g of the title compound, melting at 80.2° to 82.9° C.

Provenance & Evidence