HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 3-(4-Phenylphenoxy)-2-hydroxypropylazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Methyl formate | HCID 7865 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 1-(Biphenyl-4-yloxy)-2,3-epoxypropane | HCID 107325 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-(4-Phenylphenoxy)-2-hydroxypropylazide | HCID 21474768 | 86.5% |
Reaction Steps
A procedure similar to that described in Preparation 12 was repeated, except that 3.00 g of 4-phenylphenoxymethyloxirane (prepared as described in Preparation 82), 4.23 g of sodium azide, 15 ml of methyl formate and 90 ml of an 8:1 by volume mixture of methanol and water were used, to give 3.09 g of the title compound, melting at 72.2° to 73.9° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05688823 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-4161989416eb4325a732b9e1a4f7b718 |
| Source note | uspto-grants-1997_11 |