反应详情

6.6 g (26.8 mmol) of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylacetic acid and 20 ml of thionyl chloride are heated to reflux until gaseous evolution has ceased. The mixture is evaporated to dryness and 7.1 g (100%) of the crude acid chloride are obtained, which product is used for the next step of the synthesis without further treatment.

1. temperatureto reflux until gaseous evolution
2. customThe mixture is evaporated to dryness and 7.1 g (100%) of the crude acid chloride
3. customare obtained
4. customwhich product is used for the next step of the synthesis without further treatment