HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2294591Generated: October 28, 2026
Ethanol → 1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanol
https://huagongshe.com/reaction/2294591
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Acetoxy-1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)ethane | HCID 21474567 | — |
| Solvent | Phosphate | HCID 1061 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanol | HCID 21474499 | 88% |
| Product | Acetoxy-1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)ethane | HCID 21474567 | 73% |
Reaction Steps
6 g of (±)-acetoxy-1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)ethane, suspended in a mixture of 100 ml of phosphate buffer (0.3M, pH 7) and 1 ml of chloroform, are treated with 0.87 g of Amano P30 lipase with stirring at 40° C. for 3 days. 2.06 g (88%) of the expected product, melting point 61°-2° C. (αD =+27°; c=1, ethanol) and 2.2 g (73%) of acetoxy-1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)ethane are isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05688817 |
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| Source dataset | uspto-grants-1997_11 |
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| ORD ID | ord-1a8042f86fb6432eb30a6b8012f44f3b |
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| Source note | uspto-grants-1997_11 |
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