HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dichlorobenzene → Methyl 4-hydroxy-3-propylbenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dichlorobenzene | HCID 4685 | — |
| Reactant | Methylparaben | HCID 7456 | — |
| Product | Methyl 4-hydroxy-3-propylbenzoate | HCID 11805593 | — |
Reaction Steps
The synthesis begins with the allylation of readily available methyl-4-hydroxybenzoate (Scheme 1). The allylated phenol is then thermally rearranged in dichlorobenzene and subsequently hydrogenated to provide the desired Methyl-4-hydroxy-3-n-propylbenzoate in good overall yield. ##STR27##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05688974 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-f565139ad4a54453b845b6bd36afe5f1 |
| Source note | uspto-grants-1997_11 |