(1S,2R,3S)-3-amino-4-cyclohexyl-1-cyclopropyl-1,2-butanediol → HCID 22879395, compound

Participants

Reaction Steps

In an analogous manner to that described in Example 4, by condensing N-[(S)-α-[(tert-butylsulphonyl)methyl]hydrocinnamoyl]-1-(2,4-dinitrophenyl)-L-histidine with (1S,2R,3S)-3-amino-4-cyclohexyl-1-cyclopropyl-1,2-butanediol there is obtained (S)-α-[(S)-α-[(tert-butylsulphonyl)methyl]hydrocinnamamido]-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-1-(2,4-dinitrophenyl)imidazole-4-propionamide as a yellow solid; MS: 797 (M+H)+.

Provenance & Evidence