HCID 22879349, compound → HCID 22879345, compound

Participants

Reaction Steps

A suspension of 250 mg (0.48 mmol) of 3-[(benzyloxy)carbonyl]-N-[(tert-butoxy)carbonyl]-N-[-(1-tert-butoxyformamido)ethyl]-L-alanine tert-butyl ester and 50 mg of palladium/carbon (5%) in 10 ml of ethanol is hydrogenated at room temperature under normal pressure. Thereafter, the catalyst is filtered off and the solution is evaporated under reduced pressure. 1-tert-Butyl 4-hydrogen N-(tert-butoxycarbonyl)-N-[2-(1-tert-butoxyformamido)ethyl]-L-aspartate is obtained as a colourless foam: MS: 433 (M+H)+.

Provenance & Evidence