HCID 57086179, compound → HCID 22879340, compound

HRID 2294724Notes

Reaction equation

HRID 2294724 reaction equation
N[C@@H](CC1CCCCC1)[C@@H](O)C(O)CO.[CH:16]1([CH2:22][C@H:23]2[C@H:27]([C@H:28]([CH:32]3[CH2:34][CH2:33]3)[N:29]=[N+:30]=[N-:31])[O:26]C(C)(C)[N:24]2C(OC(C)(C)C)=O)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1>>[NH2:24][C@@H:23]([CH2:22][CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1)[C@@H:27]([OH:26])[C@@H:28]([N:29]=[N+:30]=[N-:31])[CH:32]1[CH2:33][CH2:34]1

Participants

3

Reactant 2

HCID 57086179HCID 57086179, compoundHCID 86751655HCID 86751655, compound

Product 1

HCID 22879340HCID 22879340, compound

Procedure

In a manner analogous to the procedure described above for the preparation of (2RS,3R,4S)-4-amino-5-cyclohexyl-1,2,3-pentanetriol, by reacting tert-butyl (4S,5R)-4-(cyclohexylmethyl)-5-[(S)-cyclopropylazidomethyl]-2,2-dimethyl-3-oxazolidinecarboxylate there is obtained (1S,2R,3S)-3-amino-1-azido-4-cyclohexyl-1-cyclopropyl-2-butanol as an oil, MS: 253 (M+H)+.

Sources & evidence

ORD record
ord-2f5b30e0bc1c4df383f92377618c6cad
Source dataset
uspto-grants-1997_11
Patent number
US05688946

Reaction notes

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