HCID 57086179, compound → HCID 67723857, compound

HRID 2294728Notes

Reaction equation

HRID 2294728 reaction equation
N[C@@H](CC1CCCCC1)[C@@H](O)C(O)CO.[CH:16]1([CH2:22][C@H:23]2[C@H:27]([C:28]([CH:30]3[CH2:32][CH2:31]3)=[O:29])[O:26]C(C)(C)[N:24]2C(OC(C)(C)C)=O)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1>>[NH2:24][C@@H:23]([CH2:22][CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1)[C@@H:27]([OH:26])[C:28]([CH:30]1[CH2:32][CH2:31]1)=[O:29]

Participants

3

Reactant 2

HCID 57086179HCID 57086179, compoundHCID 57243988HCID 57243988, compound

Product 1

HCID 67723857HCID 67723857, compound

Procedure

In a manner analogous to the procedure described in Example 24 for the preparation of (2RS,3R,4S)-4-amino-5-cyclohexyl-1,2,3-pentanetriol, starting from tert-butyl (4S,5R)-4-(cyclohexylmethyl)-5-(cyclopropylcarbonyl)-2,2-dimethyl-3-oxazolidinecarboxylate there is obtained (2R,3S)-3-amino-4-cyclohexyl-1-cyclopropyl-2-hydroxy-1-butanone, MS: 226 (M+H)+.

Sources & evidence

ORD record
ord-1264395bcb6b4b4fbc4e9ebd6dc344bb
Source dataset
uspto-grants-1997_11
Patent number
US05688946

Reaction notes

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