HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 178455617, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | (S)-alpha-[(S)-alpha-[(tert-butylsulphonyl)methyl]hydrocinnamamido]-N-[(1S,2R)-1-(cyclohexylmethyl)-3-cyclopropyl-2-hydroxy-3-oxopropyl]-1-(2,4-dinitrophenyl)imidazole-4-propionamide | HCID 22879390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178455617 | HCID 178455617 | — |
Reaction Steps
In an analogous manner to that described in Example 29, starting from (S)-α-[(S)-α-[(tert-butylsulphonyl)methyl]hydrocinnamamido]-N-[(1S,2R)-1-(cyclohexylmethyl)-3-cyclopropyl-2-hydroxy-3-oxopropyl]-1-(2,4-dinitrophenyl)imidazole-4-propionamide by treatment with potassium carbonate in methanol there is obtained (S)-α-[(S)-α-[(tert-butylsulphonyl)methyl]hydrocinnamamido]-N-[(1S,2R)-1-(cyclohexylmethyl)-3-cyclopropyl-2-hydroxy-3-oxopropyl]imidazole-4-propionamide as an amorphous solid; MS: 629 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05688946 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-8422f60b6f9b4cf4a735200bbb306953 |
| Source note | uspto-grants-1997_11 |