N-Cbz-d-alanine → HCID 178462188, compound

Participants

Reaction Steps

In an analogous manner to that described in Example 21, by replacing Boc-D-proline by N-benzyloxycarbonyl-D-alanine in the condensation with (S)-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-α-[(3-phenyl-L-alanyl)amino]imidazole-4-propionamide there was obtained benzyl [(R)-1-[[(S)-α-[[(S)-1-[[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]carbamoyl]-2-imidazol-4-ylethyl]carbamoyl]phenethyl]carbamoyl]ethyl]carbamate as an amorphous solid, MS: 717 (M+H)+.

Provenance & Evidence