HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl (RS)-alpha-[(tert-butylsulfonyl)methyl]hydrocinnamate → (S)-alpha-[[(Cyclopropylmethyl)sulphonyl]methyl]hydrocinnamic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl (RS)-alpha-[(tert-butylsulfonyl)methyl]hydrocinnamate | HCID 14158057 | — |
| Reactant | ethyl (RS)-alpha-[[(cyclopropylmethyl)sulphonyl]methyl]hydrocinnamate | HCID 86751664 | — |
| Product | (S)-alpha-[[(Cyclopropylmethyl)sulphonyl]methyl]hydrocinnamic acid | HCID 86751663 | — |
Reaction Steps
This compound was prepared analogously to Example 1d) by the enzymatic hydrolysis of ethyl (RS)-α-[[(cyclopropylmethyl)sulphonyl]methyl]hydrocinnamate which, in turn, was prepared analogously to the synthesis of ethyl (RS)-α-[(tert-butylsulphonyl)methyl]hydrocinnamate described in EPA 0236734 by replacing tert-butylthiol by cyclopropylmethylthiol, MS: 282 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05688946 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-552370714889440da57331d7957e730b |
| Source note | uspto-grants-1997_11 |