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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2294879Generated: October 30, 2026

Hydrochloric Acid → 1-[(5-Methoxychroman-3-YL)methyl]-4-benzylpiperazine

https://huagongshe.com/reaction/2294879

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1-[(5-Methoxychroman-3-yl)carbonyl]-4-benzylpiperazineHCID 10808905—
Reactant1-[(5-Fluoro-2,3-dihydrobenzofur-2-yl)carbonyl]-4-benzylpiperazineHCID 21472261—
Product1-[(5-Methoxychroman-3-YL)methyl]-4-benzylpiperazineHCID 1061800442%

Reaction Steps

By carrying out the preparation as in Example 1, but replacing 1-[(5-fluoro-2,3-dihydrobenzofur-2-yl) carbonyl]-4-benzylpiperazine with the hydrochloride of 1-[(5-methoxychroman-3-yl) carbonyl]-4-benzylpiperazine obtained in Stage A, the title product is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05691340
Source datasetuspto-grants-1997_11
ORD IDord-6dcf399e37ea4e1ab296018862098b1c
Source noteuspto-grants-1997_11