Sodium Bicarbonate → HCID 21472354, compound

Participants

Reaction Steps

0.57 g (2.02 mmole) of the compound obtained in step 7 was dissolved in 5 ml of 3% HCl/MeOH and heated to reflux for 30 minutes. The reaction solution was cooled and thereto was added saturated NaHCO3 solution. The resultant was extracted with ethyl acetate. The organic layer was dried over Na2SO4, concentrated under reduced pressure and purified with column chromatography (hexane:ethyl acetate=1:1) to obtain 0.61 g of the title compound (yield 92%).

Provenance & Evidence