4-Iodobenzoic acid → 4-Iodobenzoyl chloride

Participants

Reaction Steps

A mixture of 4-iodobenzoic acid (5 g) and thionyl chloride (30 ml) was heated at 70°-80° C. for 2 hours. The reaction mixture was cooled, the thionyl chloride evaporated and the resulting oil was azeotroped with toluene to give 4-iodobenzoyl chloride (5.38 g) as a solid which was used without further purification.

Provenance & Evidence