HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 4-(3,4-Dichlorophenyl)oxane-2,6-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | HCID 18475290 | HCID 18475290 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-(3,4-Dichlorophenyl)oxane-2,6-dione | HCID 54363942 | 92% |
Reaction Steps
Heat a combination of the product of Step 2 (100 g) and acetyl chloride (300 mL) at reflux for 5 hours. Cool the reaction mixture, azeotrope with toluene, and concentrate under reduced pressure. Slurry he residue with Et2O (250 mL) and filter to afford 3-(3,4-dichlorophenyl)-glutaric anhydride (86 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05691362 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-e49e04efd7574a81aa17a46b338ffe89 |
| Source note | uspto-grants-1997_11 |