HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Acetate → 5-[(3,5-Di-2-propenyl-4-hydroxyphenyl)-methylene]-2-thioxo-4-thiazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | Rhodanine | HCID 1201546 | — |
| Reactant | 3,5-Di-(2-propenyl)-4-hydroxybenzaldehyde | HCID 12047778 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-[(3,5-Di-2-propenyl-4-hydroxyphenyl)-methylene]-2-thioxo-4-thiazolidinone | HCID 54005288 | 94.6% |
Reaction Steps
3,5-di-(2-propenyl)-4-hydroxybenzaldehyde (50.5 g), 36.6 g of rhodanine and 164 g of sodium acetate were heated together at reflux temperature in 1.25 liter of acetic acid for 14.5 hours. The resultant solution was cooled, poured into 2 l of ice water to yield, upon separation, about 75 g of 5-[(3,5-di-2-propenyl-4-hydroxyphenyl)methylene]-2-thioxo-4-thiazolidinone, m.p. 157°-160° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05691367 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-9ce11ec954b84df5873e6eb5f1d30ca8 |
| Source note | uspto-grants-1997_11 |