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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2295176Generated: October 30, 2026

Morpholine → 5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester

https://huagongshe.com/reaction/2295176

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant5-Chlorocarbonyl-pyridine-2-carboxylic acid methyl esterHCID 15121177—
Product5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl esterHCID 20622307—

Reaction Steps

In step B, the acid chloride (2) is amidated with morpholine by techniques and procedures well known and appreciated by one of ordinary skill in the art to provide the corresponding 5-(morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester (3).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05691368
Source datasetuspto-grants-1997_11
ORD IDord-a4d0ad80d3014d3581898ee06e834c18
Source noteuspto-grants-1997_11