Phosgene → 2-Chloro-3-pyridinesulfonylisocyanate

Participants

Reaction Steps

To 125 ml of dry xylene was added with stirring 20.7 g of 2-chloro-N-(butylcarbamoyl)-3-pyridinesulfonamide. This solution was heated to reflux, and phosgene added until no further uptake of this gas was observed. It was then cooled, filtered and the solvent removed in vacuo to yield 2-chloro-3-pyridinesulfonylisocyanate as an oil Bp 108°-110° (0.7 mm Hg) and showing a sharp absorption peak in the infrared region at 2220 cm-1.

Provenance & Evidence