Nitrogen → HCID 20474990, compound

Participants

Reaction Steps

68.70 g (0.50 mol) of phosphorus trichloride in 50 ml of toluene were added dropwise with vigorous stirring, in the course of 1 hour, to a solution of 95.15 g (0.50 mol) of 2,2-bis-hydroxymethylpropionic acid butyl ester in 250 ml of toluene at 5°-10° C. The reaction mixture was subsequently stirred for 1 hour without cooling in a water-jet vacuum, during which time a gentle flow of N2 was fed in; the solvent was then distilled off in vacuo (bath temperature=50° C./15-20 mm Hg), and the residue was purified by vacuum distillation. The product obtained was in the form of a colourless liquid; nD20 =1.4701; b.p. 113°-115° C./0.1 mm Hg.

Provenance & Evidence