epsilon-CAPROLACTONE → 1-Nonylazepan-2-one

HRID 2295267Notes

Reaction equation

HRID 2295267 reaction equation
[C:1]1(=O)[O:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]>>[CH2:10]([N:9]1[CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1=[O:7])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

3

Reactant 2

HCID 10401epsilon-CAPROLACTONEHCID 16215Nonylamine

Product 1

HCID 128332631-Nonylazepan-2-oneYield 26%

Procedure

Following example 5, heating 22.83 g (0.2 M) of 6-hexanolactone and 28.65 g (0.2 M) of 1-aminononane at 180° for 20 hours gave 11.5 g (26%) of product; b.p. 155°-165°/0.6 mm.

Sources & evidence

ORD record
ord-82567e7a3a964dd1aaffbee30872a797
Source dataset
uspto-grants-1984_01
Patent number
US04424210

Reaction notes

Loading…