Brucine → Ephedrine

HRID 2295342Notes

Reaction equation

HRID 2295342 reaction equation
CO[C:3]1[CH:4]=[C:5]2[C@@:13]34[C@@H]5C[C@H]6C(CN5CC3)=CCO[C@H]3C[C:23](=O)[N:11]([C@H:12]4[C@@H:20]63)[C:6]2=[CH:7][C:8]=1OC.FC1C=CC2S(=[O:41])C3C=C(C(O)=O)C=CC=3C=CC=2C=1>>[CH3:20][C@H:12]([NH:11][CH3:23])[C@H:13]([OH:41])[C:5]1[CH:4]=[CH:3][CH:8]=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 442021BrucineHCID 178524101HCID 178524101, compound

Product 1

HCID 9294Ephedrine

Procedure

The brucine salt of (+) 7 or 8-fluorodibenzo[b,f]thiepin-3-carboxylic acid-5-oxide.

Sources & evidence

ORD record
ord-81ac810873e54944a2ba6359cc5d4b25
Source dataset
uspto-grants-1984_01
Patent number
US04424355

Reaction notes

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