Sodium Carbonate → HCID 178434135, compound

HRID 2295348Notes

Reaction equation

HRID 2295348 reaction equation
Cl.CC1NC2C=NC=CC=2NN=1.FC(F)(F)C1C=C(C=CC=1)C(Cl)=O.Cl.[CH3:27][C:28]1[NH:33][C:32]2[CH:34]=[N:35][CH:36]=[CH:37][C:31]=2[N:30]([C:38](=[O:49])[C:39]2[CH:44]=[CH:43][CH:42]=[C:41]([C:45]([F:48])([F:47])[F:46])[CH:40]=2)[N:29]=1.C(=O)([O-])[O-].[Na+].[Na+]>>[CH3:27][C:28]1[NH:33][C:32]2[CH:34]=[N:35][CH:36]=[CH:37][C:31]=2[N:30]([C:38](=[O:49])[C:39]2[CH:44]=[CH:43][CH:42]=[C:41]([C:45]([F:48])([F:47])[F:46])[CH:40]=2)[N:29]=1

Participants

5

Reactant 4

HCID 10340Sodium CarbonateHCID 752573-(Trifluoromethyl)benzoyl chlorideHCID 178433915HCID 178433915, compoundHCID 178434136HCID 178434136, compound

Product 1

HCID 178434135HCID 178434135, compoundYield 85%

Procedure

1.84 g (0.01 moles) of 3-methyl-1,4-dihydropyrido[3,4-e]-as-triazine hydrochloride are reacted with 10.4 g (0.05 moles) of m-trifluoromethyl-benzoyl chloride as described in Example 2. The resulting 3-methyl-1-(3'-trifluoromethylbenzoyl)-1,4-dihydropyrido[3,4-e]-as-triazine hydrochloride is treated with an aqueous solution of sodium carbonate to obtain 3-methyl-1-(3'-trifluoromethyl-benzoyl)-1,4-dihydropyrido[3,4-e]-as-triazine with a yield of 85%; m.p.: 210°-211° C.

Sources & evidence

ORD record
ord-47ec0d28dda9403184683c4a55a7003c
Source dataset
uspto-grants-1984_01
Patent number
US04424351

Reaction notes

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