Salicyloyl chloride → HCID 13136421, compound

HRID 2295356Notes

Reaction equation

Cl.[N:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[NH:9][NH:10][C:11]2[CH:17]=[CH:16][N:15]=[CH:14][C:12]=2[N:13]=1.[C:18]([Cl:27])(=[O:26])[C:19]1[C:20](=[CH:22][CH:23]=[CH:24][CH:25]=1)[OH:21]>>[ClH:27].[C:18]([N:10]1[C:11]2[CH:17]=[CH:16][N:15]=[CH:14][C:12]=2[N:13]=[C:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][N:2]=2)[NH:9]1)(=[O:26])[C:19]1[C:20](=[CH:22][CH:23]=[CH:24][CH:25]=1)[OH:21]

Participants

Reactant 2

HCID 74041Salicyloyl chloride

HCID 20475262HCID 20475262, compound

Product 1

HCID 13136421HCID 13136421, compoundYield 78%

Procedure

2.46 g (0.01 moles) of 3-(2-pyridyl)-1,2-dihydropyrido[3,4-e]-as-triazine hydrochloride are reacted with salicyloyl chloride as described in Example 2 to obtain 1-salicyloyl-3-(2-pyridyl)-1,2-dihydropyrido[3,4-e]-as-triazine hydrochloride with a yield of 78%; m.p.: 219°-220° C.

Sources & evidence

ORD record: ord-4c765b6f8aa54080ba147d6f3a25670b
Source dataset: uspto-grants-1984_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04424351

Reaction notes

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