HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → Aklomide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Benzoyl chloride, 2-chloro-4-nitro- | HCID 81522 | — |
| Product | Aklomide | HCID 2075 | 90% |
Reaction Steps
Thereafter, 2-chloro-4-nitrobenzoyl chloride (450 g, 2.1 m) was added dropwise to a stirred 28% ammonia solution (2,000 ml) at below room temperature between 9° and 16° C. The precipitated reaction mixture was washed with water and 30% methanol and then vacuum-dried to yield 2-chloro-4-nitrobenzamide (379 g, 90%, mp 168°-170° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04424371 |
| Source dataset | uspto-grants-1984_01 |
| ORD ID | ord-9cec857d21fd40069e2cb33d97c7ca65 |
| Source note | uspto-grants-1984_01 |