Ammonia → HCID 13057419, compound

HRID 2295386Notes

Reaction equation

HRID 2295386 reaction equation
[CH3:1][S:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10](Cl)(=[O:12])=[O:11].[NH3:14]>C(Cl)Cl>[CH3:1][S:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10]([NH2:14])(=[O:12])=[O:11]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 13057418HCID 13057418, compound

Product 1

HCID 13057419HCID 13057419, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 26 g (50% pure, 55 mmol) of o-methylthiomethylbenzenesulfonyl chloride in 250 ml of methylene chloride was added 4.5 ml of anhydrous ammonia at 0°-5° over 1 hour. Stirring was continued at 0°-5° C. for 2 hours. The solid precipitate was filtered off and the filtrate was evaporated to dryness to afford 24.8 g of orange residue. The crude product was triturated in ether, resulting in light pink crystals: m.p. 119°-124° C.

Workup

  1. filtrationThe solid precipitate was filtered off
  2. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-4f2a25e6fab448849d4fa5f0c92469f4
Source dataset
uspto-grants-1984_01
Patent number
US04424377

Reaction notes

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