Water → HCID 86739174, compound

HRID 2295479Notes

Reaction equation

HRID 2295479 reaction equation
[O-2].[Zn+2:2].[CH3:3][O:4][C:5](=[O:13])[C@H:6]([CH2:8][CH2:9][C:10]([O-:12])=[O:11])[NH2:7].[CH3:14][O:15][C:16](=[O:24])[CH2:17][CH2:18][C@@H:19]([C:21]([OH:23])=[O:22])[NH2:20].O>C1(C)C=CC=CC=1>[CH3:14][NH:7][C@H:6]([C:5]([O-:4])=[O:13])[CH2:8][CH2:9][C:10]([O-:12])=[O:11].[CH3:3][NH:20][C@H:19]([C:21]([O-:23])=[O:22])[CH2:18][CH2:17][C:16]([O-:15])=[O:24].[Zn+2:2].[Zn+2:2]

Participants

6

Reactant 4

HCID 962WaterHCID 686625-Methyl hydrogen L-glutamateHCID 3007857Zinc OxideHCID 70699452HCID 70699452, compound

Product 1

HCID 86739174HCID 86739174, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Zinc bis(methyl-glutamate) was prepared by reacting 12.2 grams of zinc oxide and 48.3 grams of monomethyl-glutamate also known in the art as glutamic acid 5-methyl ester as named in C.A.S. Reg. No. 1499-55-4, pg. 458 Aldrich Catalog Handbook 1979-80 in 500 ml of toluene in a one-liter, one-neck round-bottom flask equipped with a magnetic stirrer, reflux condenser and Dean-Stark Trap. The mixture was refluxed to obtain a theoretical amount of water in the Dean-Stark Trap. A white powdery product was recovered by filtration.

Workup

  1. temperaturereflux condenser
  2. temperatureThe mixture was refluxed
  3. filtrationA white powdery product was recovered by filtration

Sources & evidence

ORD record
ord-4b77ac7ca98a46ddb7345da1fe60a889
Source dataset
uspto-grants-1984_01
Patent number
US04425280

Reaction notes

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