4-Methylphenethyl bromide → HCID 54539187, compound

HRID 2295509Notes

Reaction equation

HRID 2295509 reaction equation
[C:1]1([CH3:10])[CH:6]=[CH:5][C:4]([CH2:7][CH2:8]Br)=[CH:3][CH:2]=1.[C:11]([OH:17])(=[O:16])[C:12](=[N:14][OH:15])[CH3:13]>>[C:1]1([CH3:10])[CH:6]=[CH:5][C:4]([CH2:7][CH2:8][O:15][N:14]=[C:12]([CH3:13])[C:11]([OH:17])=[O:16])=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 5706804-Methylphenethyl bromideHCID 63989592-(Hydroxyimino)propanoic acid

Product 1

HCID 54539187HCID 54539187, compoundYield 41%

Procedure

2-p-Tolylethyl bromide and pyruvic acid oxime are reacted by the process of Example 1 and the reaction mixture is evaporated when the reaction is complete. The residue is taken up in a little water, washed with diethyl ether and the aqueous solution is acidified. The precipitate obtained is filtered off with suction and dried to give a yield of 41% of theory of 2-(2-p-tolylethyloxyimino)-propionic acid; m.p. 106°-108° C.

Workup

  1. customthe reaction mixture is evaporated when the reaction
  2. washwashed with diethyl ether
  3. customThe precipitate obtained
  4. filtrationis filtered off with suction
  5. customdried

Sources & evidence

ORD record
ord-5926d484abfb4bb590e56ed0ae664c80
Source dataset
uspto-grants-1984_01
Patent number
US04425360

Reaction notes

Loading…