HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dimethoxybenzene → 3,5-Dimethoxytoluene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dimethoxybenzene | HCID 9025 | — |
| Reactant | 1,3-Cyclohexanedione | HCID 10434 | — |
| Reactant | 5-Methylcyclohexane-1,3-dione | HCID 458095 | — |
| Product | 3,5-Dimethoxytoluene | HCID 77844 | 60% |
Reaction Steps
In contrast cyclohexane-1,3-dione (R2 to R4 are H), for example, can be converted in 76% yield, to 1,3-dimethoxybenzene of type Ic over a Cu2O/thionyl chloride catalyst in methanolic solution. A 60% yield of 1,3-dimethoxy-5-methyl-benzene is obtained as the main product from 5-methyl-cyclohexane-1,3-dione under the same conditions.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04426332 |
| Source dataset | uspto-grants-1984_01 |
| ORD ID | ord-64c14d6b03f84413a38c3ab9a3018583 |
| Source note | uspto-grants-1984_01 |