HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2295751Generated: October 29, 2026
Hydrochloric Acid → 2-Sulfamoyl-1,3-benzothiazol-5-yl benzoate
https://huagongshe.com/reaction/2295751
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 29927-14-8 | HCID 121595 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Sulfamoyl-1,3-benzothiazol-5-yl benzoate | HCID 53680645 | — |
Reaction Steps
To a stirred solution of 5-hydroxy-2-benzothiazolesulfonamide (7.0 g., 0.03 mole), triethylamine (4.2 ml., 0.03 mole) and 4-dimethylaminopyridine (200 mg., catalyst) in dimethylformamide (25 ml.) is added benzoyl chloride (1.4 g., 0.01 mole). The reaction mixture is stirred at 25° C. for 11/2 hours and then poured into ice water (150 ml.) containing excess hydrochloric acid to give 2-sulfamoyl-5-benzothiazolyl benzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04426388 |
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| Source dataset | uspto-grants-1984_01 |
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| ORD ID | ord-181723a8139f4be4998315c7db567985 |
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| Source note | uspto-grants-1984_01 |
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